GPCRs: Structure, Function, and Drug Discovery

★★★★★ 4.9 120 reviews

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Management number 233473615 Release Date 2026/06/27 List Price $52.32 Model Number 233473615
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GPCRS: Structure, Function, and Drug Discovery provides a comprehensive overview of recent discoveries and our current understanding of GPCR structure, signaling, physiology, pharmacology and methods of study. In addition to the fundamental aspects of GPCR function and dynamics, international experts discuss crystal structures, GPCR complexes with partner proteins, GPCR allosteric modulation, biased signaling through protein partners, deorphanization of GPCRs, and novel GPCR-targeting ligands that could lead to the development of new therapeutics against human diseases. GPCR association with, and possible therapeutic pathways for, retinal degenerative diseases, Alzheimer’s disease, Parkinson’s disease, cancer and diabetic nephropathy, among other illnesses, are examined in-depth.Addresses our current understanding and novel advances in the GPCR field, directing readers towards recent finding of key significance for translational medicineCombines a thorough discussion of structure and function of GPCRs with disease association and drug discoveryFeatures chapter contributions from international experts in GPCR structure, signaling, physiology and pharmacology Read more

ISBN10 0128162287
ISBN13 978-0128162286
Edition 1st
Language English
Publisher Academic Press
Dimensions 8.5 x 1.18 x 10.87 inches
Item Weight 3.45 pounds
Print length 500 pages
Publication date September 26, 2019

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